Antagonists & inhibitors

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An antagonist is a drug or chemical that reduces the effect of an agonist. Competitive antagonists bind to the same site on a receptor as the agonist but do not activate it - thereby blocking the action of the agonist. Non-competitive antagonists block the action of the agonist by binding to a different site on the receptor (an allosteric or non-agonist site). A reversible antagonist binds non-covalently and can be washed out. An irreversible antagonist binds covalently and cannot be displaced by either competing ligands or washing. Inhibitors are drugs that can bind to a protein, such as an enzyme and decrease its activity. Researchers can save up to 50% on competitive antagonists, non-competitive antagonists, reversible and irreversible antagonists, and inhibitors from Hello Bio - they are up to half the price of other suppliers.

8 Items

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  1. Description:

    Potent and ATP-competitive GSK-3β inhibitor

    Purity:

    >98%

    Pack:
    5mg
    Price:
    $482
    Qty:
  2. BIO (HB1259)

    Description:

    Potent GSK-3α/β inhibitor. Maintains ESC self-renewal and pluripotency.

    Purity:

    >98%

    Pack:
    10mg
    Price:
    $283
    Qty:
    Pack:
    25mg
    Price:
    $631
    Qty:
  3. CHIR 99021 (HB1261)

    Description:

    Potent, selective GSK3 inhibitor and Wnt signaling activator. Commonly used in organoid production and involved in reprogramming MEFs to IPSCs and fibroblasts to mature neurons.

    Purity:

    >98%

    Pack:
    1mg
    Price:
    $48
    Qty:
    Pack:
    2mg
    Price:
    Qty:
    Pack:
    5×2mg
    Price:
    $180
    Qty:
    Pack:
    10mg
    Price:
    $175
    Qty:
    Pack:
    5mg
    Price:
    $112
    Qty:
    Pack:
    25mg
    Price:
    $427
    Qty:
    Pack:
    50mg
    Price:
    $727
    Qty:
    Pack:
    10mM (1mL in DMSO)
    Price:
    $121
    Qty:
  4. Description:

    Potent, selective GSK3 inhibitor and Wnt signaling activator. Commonly used in organoid production and involved in reprogramming MEFs to IPSCs and fibroblasts to mature neurons. Water soluble.

    Purity:

    >98%

    Pack:
    10mg
    Price:
    $220
    Qty:
    Pack:
    50mg
    Price:
    $879
    Qty:
  5. Pack:
    50mg
    Price:
    $736
    Qty:
  6. Description:

    GSK-3β inhibitor

    Purity:

    >97%

    Pack:
    1mg
    Price:
    $180
    Qty:
  7. SB 216763 (HB1272)

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    Description:

    Potent, selective cell permeable GSK-3 inhibitor. Maintains mESCs and promotes retinal stem cells proliferation.

    Purity:

    >98%

    Pack:
    10mg
    Price:
    $130
    Qty:
    Pack:
    50mg
    Price:
    $558
    Qty: