Antagonists & inhibitors
An antagonist is a drug or chemical that reduces the effect of an agonist. Competitive antagonists bind to the same site on a receptor as the agonist but do not activate it - thereby blocking the action of the agonist. Non-competitive antagonists block the action of the agonist by binding to a different site on the receptor (an allosteric or non-agonist site). A reversible antagonist binds non-covalently and can be washed out. An irreversible antagonist binds covalently and cannot be displaced by either competing ligands or washing. Inhibitors are drugs that can bind to a protein, such as an enzyme and decrease its activity. Researchers can save up to 50% on competitive antagonists, non-competitive antagonists, reversible and irreversible antagonists, and inhibitors from Hello Bio - they are up to half the price of other suppliers.
- Description:
Antibody to βIII Tubulin - cytoskeletal protein used as a neuronal marker. Part of the ValidAb™ range of highly validated, data-rich antibodies.
Host: MouseClonality: MonoclonalReactivity Tested: Mouse, Rat Anti-β-tubulin antibody ValidAbTM (HB6491)
Description:Antibody to β-tubulin - cytoskeletal component widely used for imaging microtubules and as a loading control. Part of the ValidAb™ range of highly validated, data-rich antibodies.
Host: MouseClonality: MonoclonalReactivity Tested: Mouse, Rat, HumanAnti-c-Fos antibody ValidAbTM (HB8006)
Description:Antibody to c-Fos - an immediate early gene used as a marker of neuronal activity. Part of the ValidAb™ range of highly validated, data-rich antibodies.
Host: MouseClonality: MonoclonalReactivity Tested: MouseAnti-Calretinin antibody ValidAbTM (HB6494)
Description:Antibody to Calretinin - calcium binding protein used as a marker for an inhibitory interneuron subtype. Part of the ValidAbâ„¢ range of highly validated, data-rich antibodies.
Host: RabbitClonality: PolyclonalReactivity Tested: Mouse, Rat