Antagonists & inhibitors
An antagonist is a drug or chemical that reduces the effect of an agonist. Competitive antagonists bind to the same site on a receptor as the agonist but do not activate it - thereby blocking the action of the agonist. Non-competitive antagonists block the action of the agonist by binding to a different site on the receptor (an allosteric or non-agonist site). A reversible antagonist binds non-covalently and can be washed out. An irreversible antagonist binds covalently and cannot be displaced by either competing ligands or washing. Inhibitors are drugs that can bind to a protein, such as an enzyme and decrease its activity. Researchers can save up to 50% on competitive antagonists, non-competitive antagonists, reversible and irreversible antagonists, and inhibitors from Hello Bio - they are up to half the price of other suppliers.
SB 269970 hydrochloride (HB1684)
Description:Potent, selective 5-HT7 receptor antagonist
Purity:>98%
SCH 23390 hydrochloride (HB1643)
Description:Potent, selective D1-like receptor antagonist
Purity:>98%
SKF 83566 hydrobromide (HB1863)
Description:Potent, selective D1-like receptor antagonist
Purity:>98%
Spiperone hydrochloride (HB1656)
Description:Selective D2-like receptor antagonist. 5-HT2A antagonist.
Purity:>98%
Spironolactone (HB2799)
Description:Mineralocorticoid and androgen receptor antagonist
Purity:>98%
SR 95531 hydrobromide (Gabazine) (HB0901)
Description:Selective, competitive GABAA receptor antagonist
Purity:>98%
(S)-(-)-Sulpiride (HB1836)
Description:Selective D2-like receptor antagonist. Active enantiomer.
Purity:>99%
(RS)-(±)-Sulpiride (HB1835)
Description:Standard D2-like dopamine receptor antagonist
Purity:>98%
Talampanel (HB0600)
Description:Selective, non-competitive AMPA / kainate receptor antagonist
Purity:>98%