Agonists & activators
An agonist or activator, is a drug or chemical that binds to and activates a protein, such as receptor or enzyme. Full agonists have high efficacy, eliciting a full response whilst occupying a small proportion of receptors. Partial agonists have a lower efficacy and cannot produce a maximal response, even if occupying a high proportion of receptors. Inverse agonists can bind to the same receptor binding-site as an agonist, but elicit an opposite effect. Researchers can save up to 50% on activators, agonists, partial agonists and inverse agonists from Hello Bio - they are up to half the price of other suppliers.
2-APB (HB1208)
Description:IP3 receptor and store-operated channels (SOC) channel antagonist
Purity:>98%
A83-01 (HB3218)
Description:Selective TGF-βRI (ALK5), ALK4 and ALK7 inhibitor. Maintains human hiPSC self renewal, 3D growth matrix component and promotes long-term organoid growth. Aids fibroblast to NSC/cardiomyocyte reprogramming.
Purity:>98%
17-AAG (HB3599)
Description:Selective Hsp90 inhibitor. Also protects neuroprogenitor cells against apoptosis.
Purity:>98%