GABA uptake & transport
GABA transport is mediated by a family of proteins known as GABA transporters, or GATs. GABA transporters are sodium- and chloride-dependent members of the Solute Carrier Family 6 (SLC6). The GAT subtypes are GAT1 (SLC6A1), GAT2 (SLC6A13), and GAT3 (SLC6A11). Within the same family are betaine transporter, BGT1 (SLC6A12), taurine transporter, TauT (SLC6A6) and creatine transporter, CT1 (SLC6A8). Researchers can save up to 50% on GAT inhibitors, activators and modulators from Hello Bio - they are up to half the price of other suppliers.
JF-NP-26 (Caged-Raseglurant) (HB6127)
Description:Novel, inactive photocaged derivative of raseglurant which can be uncaged with violet light. Shows light-dependent analgesic activity in vivo.
Purity:>98%
- Description:
Novel, intracellular covalent chemokine CCR2 negative allosteric modulator (NAM). Binds irreversibly.
- Description:
mGlu5 negative allosteric modulator
Purity:>98%
Ro 25-6981 maleate (HB0554)
Description:Selective negative allosteric modulator of GluN2B (NR2B) containing NMDARs
Purity:>98%