Nuclear Receptors
Nuclear hormone receptors (nuclear receptors) are specialised transcription factors which bind to specific sequences of DNA of particular target genes. They regulate transcription of these target genes in response to a variety of endogenous ligands. Nuclear receptors are classified into two major subfamilies: steroid and non-steroid hormone receptors. Steroid hormone receptors include receptors for estrogen (ER), androgen, glucocorticoid, mineralocorticoid and progesterone. Examples of non-steroid hormone receptors include thyroid receptors, retinoic acid receptors and peroxisome proliferator-activated receptors (PPAR). Researchers can save up to 50% on nuclear hormone receptor agonists, antagonists and modulators from Hello Bio - they are up to half the price of other suppliers.
(+)-Abscisic acid (HB4674)
Description:Phytohormone and endogenous lanthionine synthetase C-like 2 (LANCL2) ligand
Purity:>99%
(±)-Anatoxin A fumarate (HB2023)
Description:Potent nicotinic agonist. Apoptosis inducer.
Purity:>99%
(±)-Bay K 8644 (HB1209)
Description:L-type Ca2+ channel agonist. Aids iPSCs generation from Mouse embryonic fibroblasts.
Purity:>99%
Dexamethasone (HB2521)
Description:Anti-inflammatory synthetic glucocorticoid. Induces hMSC differentiation. Apoptosis inducer.
Purity:>98%
Dexamethasone (water-soluble) (HB6020)
Description:Synthetic glucocorticoid with potent anti-inflammatory actions. Induces hMSC differentiation. Apoptosis inducer. Water soluble and suitable for cell culture.Â
Purity:>98%
- Description:
Water soluble Toll-like receptor 7 (TLR7) agonist. Stimulates cytokine production.
Purity:>98%
Loperamide hydrochloride (HB0385)
Description:Potent, selective µ-opioid receptor agonist
Purity:>99%
O-Phospho-L-serine (HB0475)
Description:Group III mGlu agonist. Increases stem cell neurogenesis.
Purity:>98%
Pam2CSK4 (HB3086)
Description:TLR2/6 activator. Induces potent NF-κB activation and cytokine production.
Pam3CSK4 (HB3428)
Description:TLR1/TLR2 agonist and potent NF-κB activator. Induces cytokine production.