Group I (mGlu5, mGlu1)
Group I metabotropic glutamate receptors (mGlu1, mGlu5) are coupled with phospholipase C (PLC) via Gq proteins; activation causes increased levels of IP3 and diacylglycerol, with intracellullar Ca2+ release and protein kinase C (PKC) activation. Group I receptors are predominantly located post synaptically. Researchers can save 50% on group I metabotropic glutamate receptor agonists, antagonists, positive allosteric modulators (PAMs) and negative allosteric modulators (NAMs) from Hello Bio - they are up to half the price of other suppliers.
- Description:
Neurotoxin, widely used to produce the 6-OHDA Parkinson’s disease model
Purity:>98%
ABT 724 trihydrochloride (HB1883)
Description:Potent dopamine D4 receptor partial agonist
Purity:>99%
Acamprosate calcium (HB0099)
Description:GABA receptor agonist and glutamatergic modulator
Purity:>98%
Alprenolol hydrochloride (HB1734)
Description:Non-selective β-adrenoceptor antagonist. Also a 5-HT1A receptor antagonist.
Purity:>99%