Group I (mGlu5, mGlu1)
Group I metabotropic glutamate receptors (mGlu1, mGlu5) are coupled with phospholipase C (PLC) via Gq proteins; activation causes increased levels of IP3 and diacylglycerol, with intracellullar Ca2+ release and protein kinase C (PKC) activation. Group I receptors are predominantly located post synaptically. Researchers can save 50% on group I metabotropic glutamate receptor agonists, antagonists, positive allosteric modulators (PAMs) and negative allosteric modulators (NAMs) from Hello Bio - they are up to half the price of other suppliers.
A 769662 (HB1351)
Description:Potent, reversible AMPK activator. Inhibits MSC proliferation.
Purity:>98%
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(+)-Abscisic acid (HB4674)
Description:Phytohormone and endogenous lanthionine synthetase C-like 2 (LANCL2) ligand
Purity:>99%
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ABT 724 trihydrochloride (HB1883)
Description:Potent dopamine D4 receptor partial agonist
Purity:>99%
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Acamprosate calcium (HB0099)
Description:GABA receptor agonist and glutamatergic modulator
Purity:>98%
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Aftin-4 (HB3741)
Description:Roscovitine-related purine with no activity on CDKs. Roscovitine control. Increases Aβ42 production.
Purity:>98%
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Aftin-5 (HB3742)
Description:Roscovitine-related purine with no activity on CDKs. Roscovitine control. Increases Aβ42 production.
Purity:>98%
