DREADD

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Designer receptors exclusively activated by designer drugs (DREADDs) are genetically engineered GPCRs that are activated by physiologically inert synthetic small molecules (designer drugs) but not their endogenous ligand. Read our DREADDs mini-review or for practical advice on using these ligands in the lab see Stability of Water-Soluble DREADD Ligands in Solution: A Technical Review and Clozapine N-Oxide (freebase) - a technical review on stability, solubility and use in the lab).

Items 1-10 of 354

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  1. 3  Reviews
    Top Reviews:
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    Description:

    Neurotoxin, widely used to produce the 6-OHDA Parkinson’s disease model

    Purity:

    >98%

    Pack:
    50mg
    Price:
    $62
    Qty:
    Pack:
    250mg
    Price:
    $116
    Qty:
    Pack:
    1g
    Price:
    $391
    Qty:
  2. A11 (HB9579)

    Description:

    ANXA1 (Annexin A1) derived peptide. Blocks ANXA1-EphA2 interaction.

    Pack:
    1mg
    Price:
    $286
    Qty:
  3. A83-01 (HB3218)

    2  Reviews
    Top Reviews:
    100% of 100
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    Description:

    Selective TGF-βRI (ALK5), ALK4 and ALK7 inhibitor. Maintains human hiPSC self renewal, 3D growth matrix component and promotes long-term organoid growth. Aids fibroblast to NSC/cardiomyocyte reprogramming.

    Purity:

    >98%

    Pack:
    5mg
    Price:
    $88
    Qty:
    Pack:
    25mg
    Price:
    $297
    Qty:
  4. Description:

    Potent dopamine D4 receptor partial agonist

    Purity:

    >99%

    Pack:
    50mg
    Price:
    $625
    Qty:
  5. Pack:
    100mg
    Price:
    $233
    Qty:
  6. Description:

    Serotonin N-acetyltransferase substrate

    Purity:

    >98%

    Pack:
    10mg
    Price:
    $91
    Qty:
    Pack:
    50mg
    Price:
    $354
    Qty:
  7. AdipoRon (HB3738)

    Description:

    Adiponectin receptor (AdipoR) agonist

    Purity:

    >98%

    Pack:
    50mg
    Price:
    $385
    Qty:
  8. Description:

    AdipoR1 and AdipoR2 agonist

    Purity:

    >98%

    Pack:
    50mg
    Price:
    $685
    Qty:
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