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Designer receptors exclusively activated by designer drugs (DREADDs) are genetically engineered GPCRs that are activated by physiologically inert synthetic small molecules (designer drugs) but not their endogenous ligand. Read our DREADDs mini-review or for practical advice on using these ligands in the lab see Stability of Water-Soluble DREADD Ligands in Solution: A Technical Review and Clozapine N-Oxide (freebase) - a technical review on stability, solubility and use in the lab).

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  1. Annexin V-PE Apoptosis Staining / Detection Kit (HB8164)

    Description:

    Detects apoptosis by staining phosphatidylserine molecules translocated to the outside of the cell membrane.

    Pack:
    100 tests
    Price:
    $370
    Qty:
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  2. Antibody Diluent (HB8223)

    Description:

    Diluent used to dilute primary antibodies or for storage

    Pack:
    125mL
    Price:
    $127
    Qty:
    Pack:
    250mL
    Price:
    $216
    Qty:
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  3. Anti-βIII Tubulin antibody ValidAbTM (HB6639)

    1  Review
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    Description:

    Antibody to βIII Tubulin - cytoskeletal protein used as a neuronal marker. Part of the ValidAb™ range of highly validated, data-rich antibodies.

    Host: Mouse
    Clonality: Monoclonal
    Reactivity Tested: Mouse, Rat
    Figure 1. β3-tubulin expression in the Purkinje cells of the cerebellum labelled by HB6639.
    Pack:
    25μg
    Price:
    $136
    Qty:
    Pack:
    100μg
    Price:
    $311
    Qty:
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  4. Anti-β-tubulin antibody ValidAbTM (HB6491)

    Description:

    Antibody to β-tubulin - cytoskeletal component widely used for imaging microtubules and as a loading control. Part of the ValidAb™ range of highly validated, data-rich antibodies.

    Host: Mouse
    Clonality: Monoclonal
    Reactivity Tested: Mouse, Rat, Human
    Figure 1. ß-Tubulin and Neurofilament L expression in cultured rat neurones
    Pack:
    25μg
    Price:
    $140
    Qty:
    Pack:
    100μg
    Price:
    $311
    Qty:
    Supporting Docs Add to Favorites

  5. Anti-GAPDH antibody ValidAbTM (HB9177)

    Description:

    Antibody to GAPDH - universal loading control for western blotting. Part of the ValidAb™ range of highly validated, data-rich antibodies.

    Host: Mouse
    Clonality: Monoclonal
    Reactivity Tested: Mouse, Rat, Human
    Figure 1. GAPDH expression in various tissue lysates and preparations.
    Pack:
    25μg
    Price:
    $136
    Qty:
    Pack:
    100μg
    Price:
    $311
    Qty:
    Supporting Docs Add to Favorites

  6. Anti-GFAP antibody ValidAbTM (HB8267)

    Description:

    Antibody to GFAP - cytoskeletal protein used as an astrocyte marker. Part of the ValidAb™ range of highly validated, data-rich antibodies.

    Host: Mouse
    Clonality: Monoclonal
    Reactivity Tested: Mouse, Rat
    Figure 1. GFAP expression in a rat cultured neurone preparation visualised using HB8267.
    Pack:
    25μg
    Price:
    $140
    Qty:
    Pack:
    100μg
    Price:
    $316
    Qty:
    Supporting Docs Add to Favorites

  7. Anti-GFAP antibody ValidAbTM (HB7592)

    Description:

    Antibody to GFAP - cytoskeletal protein used as an astrocyte marker. Part of the ValidAb™ range of highly validated, data-rich antibodies.

    Host: Goat
    Clonality: Polyclonal
    Reactivity Tested: Mouse, Rat
    Figure 1. Astrocytes in culture in a cultured rat neuron preparation.
    Pack:
    25μg
    Price:
    $197
    Qty:
    Pack:
    100μg
    Price:
    $442
    Qty:
    Supporting Docs Add to Favorites

  8. Anti-GFAP antibody ValidAbTM (HB6406)

    Description:

    Antibody to GFAP - cytoskeletal protein used as an astrocyte marker. Part of the ValidAb™ range of highly validated, data-rich antibodies.

    Host: Chicken
    Clonality: Polyclonal
    Reactivity Tested: Mouse, Rat
    Figure 1. An astrocyte surrounded by neurons in a cultured rat neuron preparation.
    Pack:
    25μL
    Price:
    $164
    Qty:
    Pack:
    100μL
    Price:
    $366
    Qty:
    Supporting Docs Add to Favorites

  9. Anti-GFAP antibody ValidAbTM (HB8001)

    Description:

    Antibody to GFAP - cytoskeletal protein used as an astrocyte marker. Part of the ValidAb™ range of highly validated, data-rich antibodies.

    Host: Rabbit
    Clonality: Polyclonal
    Reactivity Tested: Mouse, Rat
    Anti-GFAP antibody ValidAb<sup>TM</sup>
    Pack:
    25μL
    Price:
    $161
    Qty:
    Pack:
    100μL
    Price:
    $360
    Qty:
    Supporting Docs Add to Favorites

  10. Anti-GFP antibody ValidAbTM (HB8912)

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    Description:

    Antibody to GFP - green coloured fluorescent protein widely used as a tag in molecular biology. Part of the ValidAb™ range of highly validated, data-rich antibodies.

    Host: Rabbit
    Clonality: Polyclonal
    Reactivity Tested: Species Independent
    Figure 1. pEGFP-C2 transfected HEK293 cells showing co-localised staining of EGFP and HB8912.
    Pack:
    25μg
    Price:
    $136
    Qty:
    Pack:
    100μg
    Price:
    $311
    Qty:
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Biological action
  1. Buffer
  2. Kit
Applications
  1. Antineoplastic Agent
  2. Cell Culture
  3. ELISA
  4. FACS and flow cytometry
  5. fluorescence imaging
  6. ICC
  7. IF
  8. IHC
  9. live cell imaging
  10. Plant Culture
  11. Selection Agent
  12. WB
  13. IHC(IF)
  14. Histoblot
Host
  1. Mouse
  2. Rabbit
  3. Goat
  4. Chicken
Target
  1. GFAP
  2. GAPDH
  3. mCherry
  4. Neurofilament L
  5. Beta III tubulin
  6. Neurofilament M
  7. GFP
  8. MAP2
  9. β-tubulin
  10. Vimentin
  11. BrdU
  12. Histone H3
  13. Ki-67