G protein coupled receptors
G-protein-coupled receptors (also known as GPCRs, transmembrane receptors, or 7-TM receptors), are integral membrane proteins that contain seven membrane-spanning domains (helices). They are coupled to heterotrimeric G proteins on the intracellular side of the cell membrane. Ligand binding causes a conformational change in the GPCR, that is then transmitted to the G protein, activating a signal transduction pathway. Researchers can save up to 50% on GPCR receptor agonists, antagonists and allosteric modulators from Hello Bio - they are up to half the price of other suppliers.
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Amitriptyline hydrochloride (HB1794)
Description:Serotonin/norepinephrine reuptake inhibitor (SNRI)
Purity:>98%
Bicifadine hydrochloride (HB1787)
Description:Potent noradrenalin transporter antagonist. Also 5-HT and dopamine transporter antagonist.
Purity:>98%
Dapoxetine hydrochloride (HB1788)
Description:Selective serotonin reuptake inhibitor (SSRI)
Purity:>99%
(S)-Duloxetine hydrochloride (HB1806)
Description:Potent 5-HT and NA reuptake inhibitor. Also inhibits dopamine reuptake.
Purity:>99%
Escitalopram oxalate (HB1804)
Description:Selective serotonin reuptake inhibitor (SSRI)
Purity:>99%
Fluoxetine hydrochloride (HB1600)
Description:Selective 5-HT uptake inhibitor. Affects differentiation of NSCs.
Purity:>98%
Fluvoxamine maleate (HB2138)
Description:Selective serotonin reuptake inhibitor and σ1 receptor agonist
Purity:>98%
Milnacipran hydrochloride (HB1759)
Description:5-HT and norepinephrine re-uptake inhibitor (SNRI)
Purity:>99%
Paroxetine hydrochloride (HB0478)
Description:Potent, selective serotonin reuptake inhibitor. Selective GRK2 inhibitor.
Purity:>99%