Ligand-gated ion channel
Ligand-gated ion channels (also known as ionotropic receptors) are transmembrane ion channel proteins that allow passage of ions upon activation by a specific chemical. Ligand-gated ion channels include ionotropic glutamate receptors (AMPA, kainate and NMDA receptors), GABAA, GABAA-ρ, Glycine, 5-HT3, HCN, acetylcholine nicotinic and purinergic (P2X) receptors. Commonly used ligands include D-AP5, NBQX, kainic acid, and gabazine. Researchers can save up to 50% on ligand-gated ion channel (ionotropic receptor) agonists, antagonists and allosteric modulators from Hello Bio - they are up to half the price of other suppliers.
View products: Ionotropic glutamate | ACh Nicotinic | AMPA | GABAA | Glycine | 5-HT3 | Kainate | NMDA | P2X | Neuroscience Research Tools
Pifithrin-μ (HB3025)
Description:p53 inhibitor. Supresses eSC self renewal and may increase stem cell reprogramming efficiency.
Purity:>99%
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Pioglitazone hydrochloride (HB2554)
Description:Selective PPARγ agonist. Enhances mESCs proliferation and survival.
Purity:>99%
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Pluripotin (HB2223)
Description:Dual ERK1/RasGAP inhibitor. Maintains ESC self-renewal.
Purity:>98%
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PluriSln 1 (HB3573)
Description:SCD1 inhibitor. Selectively eliminates undifferentiated hPSCs from culture.
Purity:>99%
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PNU 74654 (HB0528)
Description:β-catenin inhibitor. Wnt pathway inhibitor. Promotes neural differentiation of hPSCs.
Purity:>99%
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Prostaglandin E2 (HB3460)
Description:Endogenous prostanoid. Induces hematopoietic stem cell proliferation. 3D growth matrix component and used in production of liver and prostate organoids.
Purity:>98%
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Purmorphamine (HB3412)
Description:Smo receptor agonist that activates the hedgehog pathway. Induces mesenchymal and iPSC differentiation.
Purity:>98%
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Rapamycin (HB2779)
Description:mTOR inhibitor and potent immunosuppressant. Also used in inducible gene editing methods (e.g. CRISPR/Cas9) and promotes hPSC differentiation.
Purity:>98%
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Recombinant human beta-NGF protein (HB9303)
Description:Neurotrophic factor related to BDNF, NT-3 and NT-4
