Ligand-gated ion channel
Ligand-gated ion channels (also known as ionotropic receptors) are transmembrane ion channel proteins that allow passage of ions upon activation by a specific chemical. Ligand-gated ion channels include ionotropic glutamate receptors (AMPA, kainate and NMDA receptors), GABAA, GABAA-ρ, Glycine, 5-HT3, HCN, acetylcholine nicotinic and purinergic (P2X) receptors. Commonly used ligands include D-AP5, NBQX, kainic acid, and gabazine. Researchers can save up to 50% on ligand-gated ion channel (ionotropic receptor) agonists, antagonists and allosteric modulators from Hello Bio - they are up to half the price of other suppliers.
View products: Ionotropic glutamate | ACh Nicotinic | AMPA | GABAA | Glycine | 5-HT3 | Kainate | NMDA | P2X | Neuroscience Research Tools
ISX 9 (HB3401)
Description:Neurogenic agent. Induces SVZ progenitor neuronal differentiation and cardiomyogenic differentiation.
Purity:>99%
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ITD 1 (HB3446)
Description:Selective TGF-β signaling inhibitor. Induces cardiomyocyte differentiation in ESCs.
Purity:>98%
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Ivermectin (IVM) (HB1958)
Description:α7 nicotinic acetylcholine receptor positive allosteric modulator. Activates GluCI/GlyCI chemogenetic channels. Shows antiviral activity.
Purity:>95%
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IWP 2 (HB0344)
Description:Potent Wnt pathway inhibitor and PORCN inhibitor. Suppresses R1 ESC self-renewal. Used in the production of cardiac organoids.
Purity:>98%
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IWP 4 (HB3066)
Description:Potent Wnt/β-catenin signaling inhibitor. Induces cardiomyocyte differentiation of hESCs and iPSCs.
Purity:>98%
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Jasplakinolide (HB3946)
Description:Cell permeable, non-fluorescent F-actin probe. Induces actin polymerization and stabilization.
Purity:>98%
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JC-1 (HB0791)
Description:Mitochondrial membrane potential indicator/dye. Widely used in apoptosis studies.
Purity:>95%
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JK 184 (HB3179)
Description:Downstream Hedgehog signaling pathway inhibitor. Alcohol dehydrogenase 7 inhibitor.
Purity:>99%
