Ion channels
Ion channels are specialised pore-forming membrane proteins that allow ions to pass through the channel pore. They are classifed by their gating mechanism (eg. voltage-gated, ligand-gated, cyclic-nucleotide-gated & mechanosensitive) or ion selectivity (eg. calcium, potassium, sodium, chloride, proton). Researchers can save up to 50% on selective ion channel activators and blockers from Hello Bio - they are up to half the price of other suppliers.
View products: Voltage-Gated Ion Channels | Ligand-Gated Ion Channels (Ionotropic Receptors) | Ionophores | PiezoView Resources: Ion Channel Modulators
L-Ascorbic acid (HB1238)
Description:Antioxidant. Enhances iPSC generation and increases reprogramming efficiency. Supports mesenchymal stem cell proliferation.
Purity:>99%
5-Azacytidine (HB1374)
Description:DNA methyltransferase inhibitor. Improves stem cell reprogramming efficiency and induces differentiation of MSCs into cardiomyocytes.
Purity:>98%
(±)-Bay K 8644 (HB1209)
Description:L-type Ca2+ channel agonist. Aids iPSCs generation from Mouse embryonic fibroblasts.
Purity:>99%
BIX 01294 (HB1413)
Description:Potent, selective GLP / G9a HMTase inhibitor. Potentiates iPSC induction.
Purity:>98%
BrdU (5-Bromo-2′-deoxyuridine) (HB0979)
Description:Thymidine analog. Widely used to identify proliferating cells, enhances Yamanaka factor reprogramming
Purity:>98%
CHIR 99021 (HB1261)
Description:Potent, selective GSK3 inhibitor and Wnt signaling activator. Commonly used in organoid production and involved in reprogramming MEFs to IPSCs and fibroblasts to mature neurons.
Purity:>98%
CHIR 99021 trihydrochloride (HB1262)
Description:Potent, selective GSK3 inhibitor and Wnt signaling activator. Commonly used in organoid production and involved in reprogramming MEFs to IPSCs and fibroblasts to mature neurons. Water soluble.
Purity:>98%
DBZ (Dibenzazepine) (HB3419)
Description:γ-secretase and Notch pathway inhibitor. Stimulates iPSC formation.
Purity:>99%
3-Deazaneplanocin A hydrochloride (HB1416)
Description:Histone methyltransferase inhibitor. Enhances Oct4 expression in chemically-induced pluripotent stem cells.
Purity:>98%
Kenpaullone (HB1266)
Description:Potent CDK inhibitor. Also GSK-3 inhibitor. Generates iPSCs.
Purity:>98%