Ion channels

Selective, non-peptide AT₁ antagonist

Novel, potent covalent A_2A antagonist. Binds irreversibly.

Novel, covalent Affinity-Based Probe (AfBP). Clickable antagonist for the A₂AR.

Novel, intracellular covalent chemokine CCR2 negative allosteric modulator (NAM). Binds irreversibly.

Novel, potent, selective A₃AR covalent antagonist

The first covalent hA₁AR partial agonist. Binds Irreversibly.

Novel, clickable Adenosine hA₁AR Affinity-Based Probe (AfBP).

Novel, clickable Adenosine hA₃AR Affinity-Based Probe (AfBP).

Novel Selective A_2B covalent ligand. Binds irreversibly.

Potent, highly selective mGlu_1a antagonist. Water soluble.