Histone deacetylase (HDAC)

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Histone acetylation is a key epigenetic process - it is upregulated during memory formation but downregulated in numerous neurodegenerative diseases (eg. Alzheimer's disease and Huntington's disease). There are 18 Histone Deacetylase (HDAC) enzymes that are classified into two groups, the histone deacetylase family and the sirtuin family. The histone deacetylase family is further divided into classes I, II and IV. HDAC inhibitors are a class of compounds that increase acetylation of lysine residues on histone proteins as well as other, nonhistone, proteins by inhibiting the activity of these HDAC enzymes. Researchers can save up to 50% on HDAC inhibitors from Hello Bio - they are up to half the price of other suppliers.

Items 1-10 of 209

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  1. Description:

    Phytohormone and endogenous lanthionine synthetase C-like 2 (LANCL2) ligand

    Purity:

    >99%

    Pack:
    10mg
    Price:
    $139
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    Pack:
    50mg
    Price:
    $608
    Qty:
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    Description:

    Artificial cerebrospinal fluid (aCSF)

    Pack:
    25mL
    Price:
    $103
    Qty:
  3. Actinomycin D (HB1477)

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    Description:

    RNA polymerase inhibitor. Apoptosis inducer.

    Purity:

    >98%

    Pack:
    10mg
    Price:
    $124
    Qty:
    Pack:
    5mg
    Price:
    $67
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    Pack:
    100mg
    Price:
    $884
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    Pack:
    25mg
    Price:
    $232
    Qty:
  4. AK-7 (HB3747)

    Description:

    Brain-permeable SIRT2 (sirtuin 2) inhibitor

    Purity:

    >98%

    Pack:
    25mg
    Price:
    $494
    Qty:
  5. Description:

    Competitive aminopeptidase (AP) inhibitor

    Purity:

    >98%

    Pack:
    5mg
    Price:
    $209
    Qty:
  6. Pack:
    10mg
    Price:
    $160
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  7. Pack:
    5g
    Price:
    $48
    Qty:
    Pack:
    25g
    Price:
    $161
    Qty:
  8. Anisomycin (HB2239)

    Description:

    Protein synthesis inhibitor. Potent JNK / p38 MAPK activator.

    Purity:

    >98%

    Pack:
    10mg
    Price:
    $72
    Qty:
    Pack:
    50mg
    Price:
    $279
    Qty:
    Pack:
    100mg
    Price:
    $491
    Qty:
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