Histone deacetylase (HDAC)

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Histone acetylation is a key epigenetic process - it is upregulated during memory formation but downregulated in numerous neurodegenerative diseases (eg. Alzheimer's disease and Huntington's disease). There are 18 Histone Deacetylase (HDAC) enzymes that are classified into two groups, the histone deacetylase family and the sirtuin family. The histone deacetylase family is further divided into classes I, II and IV. HDAC inhibitors are a class of compounds that increase acetylation of lysine residues on histone proteins as well as other, nonhistone, proteins by inhibiting the activity of these HDAC enzymes. Researchers can save up to 50% on HDAC inhibitors from Hello Bio - they are up to half the price of other suppliers.

Items 1-10 of 384

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  1. Description:

    Potent, highly selective iNOS inhibitor

    Purity:

    >98%

    Pack:
    25mg
    Price:
    $186
    Qty:
  2. 7BIO (HB3732)

    Description:

    Aurora B and C kinase inhibitor

    Purity:

    >99%

    Pack:
    10mg
    Price:
    $191
    Qty:
    Pack:
    50mg
    Price:
    $774
    Qty:
  3. Pack:
    10mg
    Price:
    $200
    Qty:
    Pack:
    50mg
    Price:
    $807
    Qty:
  4. AACOCF3 (HB2354)

    Description:

    Selective cPLA2 inhibitor

    Pack:
    50mg
    Price:
    $604
    Qty:
  5. Description:

    Fluorogenic tri-peptide substrate. Useful for measuring trypsin-like 20S proteasome peptidase activity.

    Purity:

    >97%

    Pack:
    5mg
    Price:
    $333
    Qty:
  6. Actinomycin D (HB1477)

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    Description:

    RNA polymerase inhibitor. Apoptosis inducer.

    Purity:

    >98%

    Pack:
    10mg
    Price:
    $124
    Qty:
    Pack:
    5mg
    Price:
    $67
    Qty:
    Pack:
    100mg
    Price:
    $884
    Qty:
    Pack:
    25mg
    Price:
    $232
    Qty:
  7. Actinonin (HB3737)

    Description:

    Broad metalloprotease inhibitor

    Purity:

    >97%

    Pack:
    25mg
    Price:
    $526
    Qty:
  8. AICAR (HB2152)

    Description:

    AMPK activator. Promotes osteogenic differentiation of bone marrow-derived MSCs.

    Purity:

    >99%

    Pack:
    25mg
    Price:
    $81
    Qty:
  9. AK-7 (HB3747)

    Description:

    Brain-permeable SIRT2 (sirtuin 2) inhibitor

    Purity:

    >98%

    Pack:
    25mg
    Price:
    $494
    Qty:
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