Target

Phosphoinositide 3-kinase (PI3K)/Akt pathway inhibitor

Pan kinase inhibitor. Potently inhibits MEK1, Cdk1, Cdk2, Cdk3 and Cdk5 and GSK-3β.

Innate defence regulator peptide

Toll-like receptor 7 (TLR7) agonist

Water soluble Toll-like receptor 7 (TLR7) agonist. Stimulates cytokine production.

Calcium ionophore. Stimulates cytokine production.

Calcium ionophore. Stimulates cytokine production.

Potent, reversible p38α MAPK inhibitor

Potent, selective mTOR inhibitor

Potent, non-selective tyrosine kinase inhibitor