Target

Antioxidant. Enhances iPSC generation and increases reprogramming efficiency. Supports mesenchymal stem cell proliferation.

Potent K_Ca1.1 channel activator

K_2P2.1 (TREK-1) modulator. Used with ML336 as part of the CATKLAMP chemogenetic strategy. Selectively and irreversibly activates TREK-1^CG* but not wild-type K_2P2.1 (TREK-1)

Selective K_Ca2.2 / K_Ca2.3 activator

Selective K_IR6 activator

Epithelial K_Ca channel activator. Promotes ESC differentiation into cardiomyocytes.

K_v7.4 channel activator

K_ir6 channel activator

K_ir6 channel activator

Selective K_v7.2 / K_v7.4 channel activator