Target

Competitive, selective group 1 mGlu antagonist

Selective, non-competitive mGlu₁ antagonist

Potent group III mGluR antagonist

Group I / II mGlu antagonist

Potent, selective, non-competitive mGlu₅ antagonist

Potent, selective, non-competitive mGlu₁ antagonist

Potent, highly selective mGlu_1a antagonist. Water soluble.

Potent, highly selective mGlu_1a antagonist

Non-selective group I and II mGluR antagonist

Non-selective group I/II mGluR antagonist