Stem cells
Stem cells are unspecialized cells that are capable of self-renewal through mitotic cell division. They may be induced to form more specialized cells by a process termed cellular differentiation.The main types of stems cells are embryonic stem cells (ESCs) found in blastocysts; adult (or somatic) stem cells, found in adult tissues, induced pluripotent stem cells (iPSCs) and cancer stem cells (CSCs). Small molecule pharmacological tools can be used to manipulate signalling pathways during the in vitro culture of stem cells. These tools can be used to target signaling pathways that control cell proliferation and differentiation. Researchers can save up to 50% on stem cell research tools from Hello Bio - they are around half the price of other suppliers.
View products: Differentiation | Organoids | Proliferation/Self-renewal | Reprogramming | Stem Cell Signaling View resources: Stem Cell Research Tools & Mini-Reviews
(+)-Abscisic acid (HB4674)
Description:Phytohormone and endogenous lanthionine synthetase C-like 2 (LANCL2) ligand
Purity:>99%
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AICAR (HB2152)
Description:AMPK activator. Promotes osteogenic differentiation of bone marrow-derived MSCs.
Purity:>99%
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L-Ascorbic acid (HB1238)
Description:Antioxidant. Enhances iPSC generation and increases reprogramming efficiency. Supports mesenchymal stem cell proliferation.
Purity:>99%
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5-Azacytidine (HB1374)
Description:DNA methyltransferase inhibitor. Improves stem cell reprogramming efficiency and induces differentiation of MSCs into cardiomyocytes.
Purity:>98%
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Azidothymidine (HB4602)
Description:Selective reverse transcriptase inhibitor with anti-HIV activity. Decreases CRISPR-mediated homology directed repair (HDR) and enhances gene knockout efficiency.
Purity:>98%
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Dexamethasone (HB2521)
Description:Anti-inflammatory synthetic glucocorticoid. Induces hMSC differentiation. Apoptosis inducer.
Purity:>98%
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Dexamethasone (water-soluble) (HB6020)
Description:Synthetic glucocorticoid with potent anti-inflammatory actions. Induces hMSC differentiation. Apoptosis inducer. Water soluble and suitable for cell culture.Â
Purity:>98%
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Doxycycline hyclate (HB4608)
Description:Broad-spectrum antibiotic. Used in inducible Tet-on/ Tet-off gene expression systems for gene editing.
Purity:>95%
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FK 506 (HB0289)
Description:Potent calcineurin phosphatase 2B inhibitor. Enhances osteoblastic differentiation in mesenchymal cells.
Purity:>99%
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(Z)-4-Hydroxytamoxifen (Z-4-OHT) (HB2508)
Description:Synthetic estrogen receptor ligand. Widely used in genome engineering (e.g. CreER/ CRISPR-Cas9).
Purity:>98%
