Cytokines, chemokines & NF-κB/I-κB
Cytokines and chemokines play an important role in inflammation and act as key modulators of inflammation by acting through a variety of pathways and interactions. Proinflammatory cytokines activate the IKK complex and closely interact with NF-κB and JAK/STAT signaling. Researchers can make big savings on Hello Bio's cytokines and chemokines modulators, our prices are around 25-50% less than other suppliers.
A83-01 (HB3218)
Description:Selective TGF-βRI (ALK5), ALK4 and ALK7 inhibitor. Maintains human hiPSC self renewal, 3D growth matrix component and promotes long-term organoid growth. Aids fibroblast to NSC/cardiomyocyte reprogramming.
Purity:>98%
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Brefeldin A (BFA) (HB2949)
Description:Reversible protein transport inhibitor. Commonly used in cytokine staining. Enhances CRISPR-mediated HDR.
Purity:>98%
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Calyculin A (HB0161)
Description:Potent, selective protein phosphatase 1 / 2A inhibitor
Purity:>98%
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CHIR 99021 (HB1261)
Description:Potent, selective GSK3 inhibitor and Wnt signaling activator. Commonly used in organoid production and involved in reprogramming MEFs to IPSCs and fibroblasts to mature neurons.
Purity:>98%
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DBZ (Dibenzazepine) (HB3419)
Description:γ-secretase and Notch pathway inhibitor. Stimulates iPSC formation.
Purity:>99%
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Fasudil hydrochloride (HB0283)
Description:ROCK and cyclic nucleotide-dependent protein kinase inhibitor
Purity:>98%
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