Cytokine Storm / Immune response signaling

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Cytokine storm describes an excessive immune response to external stimuli with the release of a large amount of pro-inflammatory cytokines. Cytokine storms occur in a range of infections and non-infectious diseases including COVID-19. The cytokine storm involves a variety of immune-related molecules such as interferon, interleukins, chemokines, CSFs and TNF-α. Increase in proinflammatory cytokines results in an influx of immune cells such as macrophages, T-Cells and neutrophils. The immune response to SARS-CoV2 infection also involves various signaling pathways. Researchers can save up to 50% on small molecules that affect cytokine storm and the immune response, as they are up to half the price of other suppliers.

View products: Angiotensin related | Cytokines, chemokines & NF-κB/I-κB | Inflammasomes | JAK/STAT | MAPK Signaling | PI3K/Akt/mTOR | Protease-Activated Receptors | TLR signaling

2 Items

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  1. Anisomycin (HB2239)

    Description:

    Protein synthesis inhibitor. Potent JNK / p38 MAPK activator.

    Purity:

    >98%

    Pack:
    10mg
    Price:
    $72
    Qty:
    Pack:
    50mg
    Price:
    $279
    Qty:
    Pack:
    100mg
    Price:
    $491
    Qty:
  2. SP600125 (HB2234)

    Description:

    Selective, ATP-competitive JNK inhibitor. Prevents BMP9-induced osteogenic MSC differentiation. Maintains stem cells in naive pluripotent state.

    Purity:

    >98%

    Pack:
    10mg
    Price:
    $74
    Qty:
    Pack:
    50mg
    Price:
    $310
    Qty: