Cytokine Storm / Immune response signaling

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Cytokine storm describes an excessive immune response to external stimuli with the release of a large amount of pro-inflammatory cytokines. Cytokine storms occur in a range of infections and non-infectious diseases including COVID-19. The cytokine storm involves a variety of immune-related molecules such as interferon, interleukins, chemokines, CSFs and TNF-α. Increase in proinflammatory cytokines results in an influx of immune cells such as macrophages, T-Cells and neutrophils. The immune response to SARS-CoV2 infection also involves various signaling pathways. Researchers can save up to 50% on small molecules that affect cytokine storm and the immune response, as they are up to half the price of other suppliers.

View products: Angiotensin related | Cytokines, chemokines & NF-κB/I-κB | Inflammasomes | JAK/STAT | MAPK Signaling | PI3K/Akt/mTOR | Protease-Activated Receptors | TLR signaling

Items 1-10 of 20

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  1. 17-AAG (HB3599)

    Description:

    Selective Hsp90 inhibitor. Also protects neuroprogenitor cells against apoptosis.

    Purity:

    >98%

    Pack:
    1mg
    Price:
    $133
    Qty:
  2. Pack:
    10mg
    Price:
    $160
    Qty:
  3. BIO (HB1259)

    Description:

    Potent GSK-3α/β inhibitor. Maintains ESC self-renewal and pluripotency.

    Purity:

    >98%

    Pack:
    10mg
    Price:
    $283
    Qty:
    Pack:
    25mg
    Price:
    $631
    Qty:
  4. Pack:
    10mg
    Price:
    $99
    Qty:
    Pack:
    50mg
    Price:
    $367
    Qty:
  5. Cyclopamine (HB2965)

    Description:

    Smo and hedgehog (Hh) signaling inhibitor. Also depletes stem like cancer cells and induces hESCs into endocrine cells.

    Purity:

    >98%

    Pack:
    1mg
    Price:
    $196
    Qty:
    Pack:
    5mg
    Price:
    $746
    Qty:
  6. Pack:
    1g
    Price:
    $110
    Qty:
  7. Pack:
    10mg
    Price:
    $168
    Qty:
  8. GANT61 (HB3394)

    Description:

    GLI antagonist. Also Hedgehog (Hh) signaling inhibitor.

    Purity:

    >98%

    Pack:
    10mg
    Price:
    $180
    Qty:
    Pack:
    50mg
    Price:
    $688
    Qty:
  9. Geldanamycin (HB3311)

    Description:

    Selective Hsp90 inhibitor. Breast cancer stem cell inhibitor.

    Purity:

    >98%

    Pack:
    5mg
    Price:
    $294
    Qty:
  10. IWP 2 (HB0344)

    Description:

    Potent Wnt pathway inhibitor and PORCN inhibitor. Suppresses R1 ESC self-renewal. Used in the production of cardiac organoids.

    Purity:

    >98%

    Pack:
    25mg
    Price:
    $359
    Qty:
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