Cytokine Storm / Immune response signaling
Cytokine storm describes an excessive immune response to external stimuli with the release of a large amount of pro-inflammatory cytokines. Cytokine storms occur in a range of infections and non-infectious diseases including COVID-19. The cytokine storm involves a variety of immune-related molecules such as interferon, interleukins, chemokines, CSFs and TNF-α. Increase in proinflammatory cytokines results in an influx of immune cells such as macrophages, T-Cells and neutrophils. The immune response to SARS-CoV2 infection also involves various signaling pathways. Researchers can save up to 50% on small molecules that affect cytokine storm and the immune response, as they are up to half the price of other suppliers.
View products: Angiotensin related | Cytokines, chemokines & NF-κB/I-κB | Inflammasomes | JAK/STAT | MAPK Signaling | PI3K/Akt/mTOR | Protease-Activated Receptors | TLR signaling
Malformin C (HB3966)
Description:Antibiotic. Potent G2 checkpoint cell cycle arrest inhibitor
Purity:>95%
MCA-AVLQSGFR-Lys(Dnp)-Lys-NH2 (HB9059)
Description:SARS-CoV Mpro FRET substrate suitable for measuring Mpro & SARS-Cov Mpro protease activity
MCC950 sodium salt (HB4636)
Description:Potent, selective NLRP3 inflammasome inhibitor
Purity:>98%
Mefloquine hydrochloride (HB9555)
Description:Cx36 and Cx50 gap channel blocker. Antimalarial, antischistosomal and antiviral.
Purity:>98%
MEGA-8 (HB3972)
Description:Non-ionic,water-soluble detergent with nondenaturing properties
Purity:>99%